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Anti-VEGF agents,including ranibizumab and pegaptanib, can cause regres-sion of the abnormal blood vessels and improvement ofvision when injected every 4–6 weeks directly into thevitreous humor of the eye; complications can includeendophthalmitis, increased IOP, traumatic cataract, andretinal detachment. (2010) Frequencyof sensory symptoms and abnormal nerve conduction studies ina sCJD Cohort.

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